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To the Editor.—
Drs. Molokhia and Portnoy certainly have a point in regard to the need to consider the epidermis and the dermis as separate entities from a biochemical aspect. It is, however, one thing to separate normal epidermis from dermis and quite another to get a reliable dermal-epidermal cleavage plane between psoriatic epidermis and dermis. In spite of many attempts we have, for a variety of reasons, never satisfactorily accomplished the latter of these tasks. It is for this reason that we clearly stated in the article that we were dealing with dermis and epidermis as a unit.Apparently Drs. Molokhia and Portnoy have developed a reliable method of dermal-epidermal separation in psoriatic tissue and we will eagerly await the histological verification of this accomplishment when it appears in the British Journal of Dermatology. It could be that their technique will be a great boon to those of us
Voorhees JJ. ZINC LEVELS IN PSORIASIS-Reply. Arch Dermatol. 1970;102(3):352. doi:10.1001/archderm.1970.04000090114024