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October 1970

Guttate Leukoderma in Darier's Disease

Author Affiliations

Houston, Tex

From the Department of Dermatology, Baylor College of Medicine, Texas Medical Center, Houston. Dr. Cornelison is now with the University of Oklahoma Medical Center, Oklahoma City.

Arch Dermatol. 1970;102(4):447-450. doi:10.1001/archderm.1970.04000100095020

Widespread guttate leukoderma associated with keratosis follicularis occurred in three patients. These lesions were not preceded by inflammatory lesions and were usually found in areas free of the greasy papules of keratosis follicularis. The white macules show virtual absence of melanin on histological examination. We believe that the association of guttate leukoderma with keratosis follicularis is more common than the scant attention in the literature would indicate.