[Skip to Content]
[Skip to Content Landing]
November 1970

Ectopic Adrenocorticotropic Hormone SyndromeAssociated With Metastatic Skin Tumors and Cushing's Syndrome

Author Affiliations

From the departments of dermatology and medicine, Hospital of the University of Pennsylvania, Philadelphia.

Arch Dermatol. 1970;102(5):556-559. doi:10.1001/archderm.1970.04000110072015

A case of the ectopic adrenocorticotropic hormone (ACTH) syndrome associated with malignancy and Cushing's syndrome was established by the recovery of an ACTH-like polypeptide from a metastatic cutaneous nodule. This communication emphasizes the capacity of neoplasms to produce a variety of hormone-like substances, and reviews the clinical and laboratory features of the ectopic ACTH-syndrome.