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Article
December 1970

Pilosebaceous Dysplasia in the Oral-Facial-Digital Syndrome

Author Affiliations

Chicago

From the Department of Dermatology and Center for Cranio-facial Anomalies, colleges of medicine and dentistry, University of Illinois, Chicago.

Arch Dermatol. 1970;102(6):598-602. doi:10.1001/archderm.1970.04000120016003
Abstract

The clinical features of eight female patients with the oral-facial-digital (OFD) syndrome, including a description of the skin and its histological and pharmacological characteristics are described. The OFD syndrome is characterized in part by a cutaneous dyplasia which includes a marked diminution in sebaceous glands, some decrease in hair follicles, and early keratinous cyst formation, which may represent maldevelopment of the pilosebaceous unit.

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