[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.211.120.181. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
December 1970

SULFONES

Author Affiliations

5420 Barnes Ave NW Seattle 98107

Arch Dermatol. 1970;102(6):694. doi:10.1001/archderm.1970.04000120112024
Abstract

To the Editor.—  In their review of drug reactions to the sulfones, Millikan and Harrell commented that they were not aware of fatalities from agranulocytosis induced by sulfones.1A recent report from Vietnam,2 where Dapsone was used as daily prophylaxis against falciparum malaria, cited 16 cases of Dapsone-induced agranulocytosis of which eight patients died. As it was estimated that well over 100,000 troops were taking the Dapsone daily, the incidence of fatalities from agranulocytosis was, of course, very low. Nonetheless, as a result of severe side effects from Dapsone, it is no longer being used routinely for falciparum malaria prophylaxis in Vietnam.

First Page Preview View Large
First page PDF preview
First page PDF preview
×