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METROPOLITAN DERMATOLOGICAL SOCIETY OF LOS ANGELES
Nov 25, 1969
Darier's Disease (Keratosis Follicularis). Presented by Richard M. Schiff, MD.
A 70-year-old white man developed numerous discrete scaly papules, predominately on the back and chest during the past two to three years. There are no family members with a similar skin problem.
Leo Indianer, MD: Hyperkeratosis, suprabasilar clefting with villi formation, retained nuclei in the area of hyperkeratosis, corps ronds, and grains are identified. Findings from histology are compatible with Darier's disease (keratosis follicularis). The patient exhibits multiple lesions at an older age than we would expect Darier's disease to begin. The question is whether this individual has true Darier's disease or a milder form that perhaps we will be diagnosing more frequently in individuals with dry, itching skin and multiple "seborrheic keratoses."Dr. Paul Hirsch: Because of the varied discussion at last month's meeting of Dr. Schiff's case of Darier's
Society Transactions. Arch Dermatol. 1970;102(6):696-703. doi:10.1001/archderm.1970.04000120114026