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Article
March 1971

HISTOGENESIS OF POROKERATOSIS

Author Affiliations

Goa Medical College, Panaji Goa, India

Arch Dermatol. 1971;103(3):342. doi:10.1001/archderm.1971.04000150112024
Abstract

To the Editor.—  It was interesting to read a communication by Reed and Leone1 in the Archives. It would be fitting to recall the original contention of Mibelli2 that porokeratosis is a disease of eccrine sweat-duct units. Recently a few authors3-6 have substantiated his well-conceived observations. It is surprising to note that the authors1 have overlooked these informative studies. It seems to have happened unintentionally. Furthermore, it would be interesting to mention that Reed and Leone1 have made a retrospective study of 35 cases of porokeratosis, which indicates that the authors have not evaluated the cases themselves clinically.I have diagnosed porokeratosis (Mibelli's disease), a rare disease, in seven patients. It is relevant to record that only in one case a positive family history was available. On the basis of clinical material seen personally, it was postulated that the disease manifests itself in two ways,

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