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Article
May 1971

Intensified Contact Sensitization to Benzyl SalicylatePhototoxic Effects of Topical Psoralen Therapy

Author Affiliations

Denver

From the Division of Dermatology, University of Colorado Medical Center, Denver.

Arch Dermatol. 1971;103(5):497-500. doi:10.1001/archderm.1971.04000170031007
Abstract

Benzyl salicylate (BS), a weak contact sensitizer, caused severe pruritus in six of 15 patients who applied it in a trioxsalen lotion. Delayed hypersensitivity to BS was enhanced by the phototoxic effects of methoxsalen. Only one of 14 control patients reacted to the BS.

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