A 71-year-old woman with chronic mucocutaneous candidiasis was found to have a benign thymoma and impaired cellular immune response. She was anergic to common skin-test antigens and she could not be sensitized to fluorodinitrobenzene, but her lymphocytes did respond in a normal manner to phytohemagglutinin and Candida albicans antigen stimulation. It is believed that this represents an acquired, adult counterpart of the congenital childhood chronic mucocutaneous candidiasis syndrome. Treatment of her thymoma has not, thus far, improved her candidiasis.
Maize JC, Lynch PJ. Chronic Mucocutaneous Candidiasis of the AdultA Report of a Patient With an Associated Thymoma. Arch Dermatol. 1972;105(1):96-98. doi:10.1001/archderm.1972.01620040064016