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February 1972

Lupus Vulgaris and Hodgkin's Disease

Author Affiliations

Oxford, England

From the Nuffield Department of Clinical Medicine, Radcliffe Infirmary, Oxford, England.

Arch Dermatol. 1972;105(2):244-246. doi:10.1001/archderm.1972.01620050054011

A case of lupus vulgaris previously well controlled by antituberculous treatment became a fulminant systemic infection three months after therapy was discontinued and coincident with the discovery of extensive Hodgkin's disease with associated anergy. The nature of the immunologic defect in Hodgkin's disease is reviewed in connection with its probable role in disseminating this patient's cutaneous tuberculosis. Reactivation or progression of treated mycobacterial infection should alert the physician to possible underlying Hodgkin's disease, which may resist diagnosis because of clinical features indistinguishable from tuberculosis.