Four members of a family had comedo-like lesions in which distinctive dykeratotic changes were found histologically. After studying the familial aspect of this disease, with discussion of the differential diagnosis, we have given it the proposed name, familial dyskeratotic comedones. To our knowledge, these are the first such cases reported in the English literature.
Carneiro SJC, Dickson JE, Knox JM. Familial Dyskeratotic Comedones. Arch Dermatol. 1972;105(2):249-251. doi:10.1001/archderm.1972.01620050059013