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March 1972


Arch Dermatol. 1972;105(3):445-452. doi:10.1001/archderm.1972.01620060079019

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Juvenile Melanoma. Presented by John T. McCarthy, MD.  This 2½-year-old girl developed a lesion on the tip of her nose three months ago. The deep, firm red nodule has grown rapidly until now it is 1 cm in diameter. A biopsy was performed, after which the lesion was curetted and the base treated with electrodesiccation.Histologically, the central portion of the specimen appears crusted and ulcerated. Other portions show patchy parakeratosis and prominent irregular acanthosis. Within the lower portions of the epidermis, at the dermal-epidermal junction, and in the subjacent cutis, one observes relatively compact anastomosing cords and nests of cells which, for the most part, tend to assume spindle shapes. Occasional multinucleated forms are identified. Mitotic figures are observed. The overall histologic features are compatible witha traumatized active compound nevus of the spindle cell type. This probably represents a variant of a juvenile melanoma. The diagnosis is believed to

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