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To the Editor.—
In 1961, Coffey et al, in the Archives (83:1014-1015, 1961), first reported the use of amphotericin B in disseminated cuta neous candidiasis. The patient was a 4-year-old girl hospitalized at the Children's Memorial Hospital, University of Oklahoma Medical Center. The purpose of this letter is to provide a progress report on the interesting developments in this patient since she was initially seen in June 1959.The patient was first treated with amphotericin B, administered intravenously, from July 3 until Aug 11, 1959. Although the possibility of a defect in immunologic response was considered, no abnormality could be demonstrated by techniques available at that time. She remained free of Candida infection until February 1960, when there was a recurrence which was treated with mycostatin topically, with temporary improvement. Because of a recrudescence of the dermal lesions, she was again hospitalized from June 15, 1960 to Aug 2,
Riley HD. A Progress Report. Arch Dermatol. 1972;105(6):927. doi:10.1001/archderm.1972.01620090091024