The development and progression of diffuse pigmentation and venous ectasia on the dorsa of the hands of a healthy middle-aged man were closely studied clinically and histologically for 21/2 years. Associated were bilateral edema of the hands, an increase in the number and size of cutaneous blood vessels, as well as a progressive increase of iron pigment in the skin of the dermis. It is proposed that these findings are an expression of a venous stasis syndrome.
Schlappner OLA, Shelley WB, Beerman H. Progressive Pigmentation and Venous Ectasia of the HandsA Stasis Syndrome. Arch Dermatol. 1972;106(2):235-237. doi:10.1001/archderm.1972.01620110067017