Incontinentia Pigmenti. Presented by Irving A. Lewe, MD.
A 6-week-old white girl had red blisters on the front of her chin at birth. About a week later, new blisters developed on her lower, and then her upper extremities. This was the mother's first pregnancy. She was treated with ampicillin for a "chest cold" with fever three weeks before delivery. Otherwise, the pregnancy and delivery were normal.Examination of the infant revealed erythematous vesicles and small bullae, many in a linear configuration, on the posteromedial surfaces of the legs, the medial surface of the thighs, and, to a lesser extent, the flexor surfaces of the forearms, and the dorsal surfaces of the wrists and hands. A few of the blisters were ruptured and covered with a sanguineous crust. A patch of scaly erythema appeared on the right side of the chin. Linear streaks and reticulated patterns of brown pigmentation were on
Leland CM. THE METROPOLITAN DERMATOLOGICAL SOCIETY OF LOS ANGELES. Arch Dermatol. 1972;106(4):587-589. doi:10.1001/archderm.1972.01620130097025