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October 1972


Arch Dermatol. 1972;106(4):587-589. doi:10.1001/archderm.1972.01620130097025

Incontinentia Pigmenti. Presented by Irving A. Lewe, MD.  A 6-week-old white girl had red blisters on the front of her chin at birth. About a week later, new blisters developed on her lower, and then her upper extremities. This was the mother's first pregnancy. She was treated with ampicillin for a "chest cold" with fever three weeks before delivery. Otherwise, the pregnancy and delivery were normal.Examination of the infant revealed erythematous vesicles and small bullae, many in a linear configuration, on the posteromedial surfaces of the legs, the medial surface of the thighs, and, to a lesser extent, the flexor surfaces of the forearms, and the dorsal surfaces of the wrists and hands. A few of the blisters were ruptured and covered with a sanguineous crust. A patch of scaly erythema appeared on the right side of the chin. Linear streaks and reticulated patterns of brown pigmentation were on

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