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October 1972

Perifollicular Xanthomatosis

Author Affiliations

Ostend, Belgium

Arch Dermatol. 1972;106(4):595-596. doi:10.1001/archderm.1972.01620130101029

To the Editor.—  I read with great interest the paper "Perifollicular Xanthomatosis" by Drs. Pirozzi and Gross (Arch Dermatol 104:431-433, 1971) in which they reported papular perifollicular xanthomata on thighs and buttocks of a patient with type IV primary hyperlipoproteinemia. They considered this clinical type of xanthoma as unusual and previously not reported.I object to this statement and I hope that no further consideration will be given to perifollicular xanthomatosis as a designation because simply eruptive xanthomata are described here.Eruptive xanthomata, usually discrete papules, arise in crops with a predilection for buttocks and thighs, on which they often originate in a follicular distribution (follicular, clinically; perifollicular, histologically). Therefore, they might resemble folliculitis. Later, by enlargement and confluence, this follicular distribution of eruptive xanthoma tends to disappear.Although this particular feature of eruptive xanthoma on thighs and buttocks may not be mentioned in standard textbooks of dermatology, it may

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