A case of angiokeratoma of Mibelli occurred in a mentally-retarded 11-year-old girl who had cerebral spastic diplegia acrocyanosis, chilblains, and recurring oral ulceration. A notable feature was the gross bone and soft tissue destruction of the fingertips. The serum IgG, IgA, and IgM levels were raised.
Dave VK, Main RA. Angiokeratoma of Mibelli With Necrosis of the Fingertips. Arch Dermatol. 1972;106(5):726-728. doi:10.1001/archderm.1972.01620140070022