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This monograph summarizes the compiled studies by the authors in seeking a correlation between the manifestation of endocrine disorders in the skin, especially hirsutism, and steroid metabolism in the skin. The authors have carried out many painstaking experiments and made a number of significant observations. Their laboratory data substantiate the hypothesis that endocrinological abnormalities are associated with variations in steroid content and metabolism in the skin. Citation of literature is extensive throughout each section, and laboratory methods useful for the study of steroids in the skin are described in the appendix at the end of the book. This volume is a valuable reference for endocrinologists, dermatologists, and steroid biochemists who are interested in basic understanding of dermatologic endocrinology.
The investigation began with the demonstration of Zimmermann chromogens in extracts of whole skin excised at surgery from the abdomen and pubic area of hirsute and nonhirsute females, as well as from
Hsia SL. Steroids in Human Skin. Arch Dermatol. 1972;106(5):775. doi:10.1001/archderm.1972.01620140103038