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January 1973

Direct Immunofluorescence of Bullous Systemic Lupus Erythematosus

Author Affiliations

USAF, Lackland, Tex; USA, Washington, DC

From the Dermatology Service, Wilford Hall Medical Center, Lackland (Tex) Air Force Base (CPT Pedro), and the Dermatology Service, Department of Medicine, Walter Reed General Hospital, Washington, DC (MAJ Dahl).

Arch Dermatol. 1973;107(1):118-120. doi:10.1001/archderm.1973.01620160086028

The importance of direct immunofluorescence in the diagnosis of bullous skin lesions is illustrated by the following report of bullous systemic lupus erythematosus (SLE). Direct immunofluorescence of the bullous lesions of SLE demonstrated the lupus band six months before the lupus erythematosus cell phenomenon became positive. Direct immunofluorescent studies may provide an important tool for the early diagnosis of SLE particularly when other tests are not helpful.