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February 1973

Vitamin A Acid in Treatment of Oral Lichen Planus

Author Affiliations

Glasgow, Scotland

From the Department of Dermatology, University of Glasgow, Glasgow, Scotland.

Arch Dermatol. 1973;107(2):277. doi:10.1001/archderm.1973.01620170085024

Seventeen patients with oral lichen planus, two of them also with lichen planus patches on the glans penis, were treated with vitamin A acid. The systemic effect resulted in regression of discrete and leukoplakia-like papules. Linear pattern of the oral mucosa and lichen-planus patches of the glans penis showed distinct involution only by topical administration of the agent. Recurrences were observed in two patients. The side effects of such treatment are mentioned.