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February 1973

Ichthyosis HystrixEpidermolytic Hyperkeratosis; Discordant in Monozygotic Twins

Author Affiliations


From the Department of Medicine (Dermatology), Ottawa Civic Hospital, University of Ottawa, Ottawa. Dr. Richards is now at North York General Hospital, Toronto.

Arch Dermatol. 1973;107(2):278-282. doi:10.1001/archderm.1973.01620170086025

Two unrelated families are presented in which only one monozygotic twin demonstrated ichthyosis hystrix, while a nontwin sibling showed ichthyosis vulgaris. Zygosity in the twins was determined by using physical traits, placental characteristics, blood typing, dermatoglyphics, and skin grafting.