A young boy had urticaria pigmentosa and the concomitant occurrence of acute lymphoblastic leukemia. It is possible that the leukemic process may be a complication of systemic urticaria pigmentosa. The various forms of leukemia that have occurred in this condition are noted.
Fromer JL, Jaffe N. Urticaria Pigmentosa and Acute Lymphoblastic Leukemia. Arch Dermatol. 1973;107(2):283-284. doi:10.1001/archderm.1973.01620170091026