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Erythroderma? Psoriasis? Lymphoma? Presented by Orlando Canizares, MD.
A 72-year-old woman developed the present condition in 1948 following a severe sunburn. An eruption appeared on her ankles and subsided slowly. New lesions appeared in 1958 about the ankles and gradually spread along the legs and thighs. She was told the diagnosis was psoriasis. After a bone marrow examination, leukemia was suspected, but subsequent examinations did not confirm this diagnosis. In 1964, a biopsy specimen of a lymph node was reported as "lymphoid and reticuloendothelial hyperplasia." Methotrexate was administered with noticeable improvement and x-ray therapy was also given. During an episode of herpes zoster, she received adrenocorticotrophic hormone (ACTH) with some improvement. At present, she is receiving 50 mg of prednisolone every day.Results of physical examination were essentially negative except for a liver edge three fingers' breadth below the costal margin on deep inspiration. The spleen was not enlarged (Dr.
Atkinson SC. NEW YORK DERMATOLOGICAL SOCIETY February 22, 1972. Arch Dermatol. 1973;107(3):450-452. doi:10.1001/archderm.1973.01620180096032