A series of alkyl-α-cyanoacrylates were investigated as dressings for friction blisters. Of the monomers tested, a viscous isoamyl-α-cyanoacrylate and pentyl cyanoacrylate seemed to be the most effective in regard to relieving pain, preventing infection, and permitting the continuation of work. Applying cyanoacrylate was found more satisfactory than using a mixture of polymyxin B sulfate, neomycin sulfate, and gramicidin (Neosporin Cream) and moleskin treatment.
Akers WA, Leonard F, Ousterhout DK, Cortese TA. Treating Friction Blisters With Alkyl-a-Cyanoacrylates. Arch Dermatol. 1973;107(4):544-547. doi:10.1001/archderm.1973.01620190020004