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Collagenosis and Raynaud Phenomenon. Presented by LT Herbert B. Allen, MC, USN.
A 43-year-old white woman had a 10-month history of swelling of eyelids and hands associated with numbness and tingling especially on cold exposure. Cold causes hands to change color from white to blue to red to normal. Some weakness in proximal muscle groups was noted, but there was no muscle tenderness. Recent pelvic examination was normal.On her initial examination, a heliotrope color of the eyelids was present. Eyelids are still swollen but not purple. Hands appear swollen and palms exhibit a redpurple discoloration.Laboratory studies disclosed the following values: hematocrit reading, 43%; white blood cell count, 9,000/cu mm, with 57% polymorphonuclear leukocytes and 43% lymphocytes; urinalysis, normal. Various x-ray films were within normal limits; doubtful lesions were seen in the sigmoid colon, but were not confirmed on colonoscopy. Blood chemistry studies, electrolytes, and protein electrophoresis were all
Goldschmidt H. PHILADELPHIA DERMATOLOGICAL SOCIETY. Arch Dermatol. 1973;107(4):621-622. doi:10.1001/archderm.1973.01620190089025