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The timing of this monograph is most appropriate since it is almost the 100-year anniversary of the initial identification of the mast cell by Ehrlich. The current text is a worthwhile addition to libraries of those interested in the basic science aspects of mast cells. Most of the material relates to mast cells in the rat. There is no attempt to make broad sweeping generalizations relating to analogous data in man.
Appropriately, the text begins with a foreword by Dr. Hans Selye, who has published extensively on the mast cell. This is followed by a short introduction and then an informative chapter on general information, which is highlighted by discussion of mast-cell transformation and the role of selected hormones therein.
Over one half of the monograph is devoted to discussion of quantitative and qualitative regulation of mast cells; much of this is based upon original work of Csaba and associates.
Orkin M. Regulation of Mast-Cell Formation. Arch Dermatol. 1973;107(4):639. doi:10.1001/archderm.1973.01620190101036