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Epidermolysis Bullosa. Presented by Staff of Harbor General Hospital.
A 5-month-old Negro boy was born to a gravida 3, para 3 mother in a full-term normal delivery. At birth, the 3.1-kg infant was covered with many blisters on the knees, arms, abdomen, buttocks, hands, cheeks, perineal area, and back. The peribullous skin was erythematous. The bullae contained yellow-orange serous fluid. Virus and bacterial cultures were negative. Scattered denuded areas were present. A positive Nikolsky sign was present in the erythematous areas. After four days of life, sepsis developed with a positive blood culture for Staphylococcus aureus. The child responded to treatment with methicillin, transfusions, and local treatment with Sulfamylon and triamcinolone cream. Over the next few weeks, the bullous lesions and denuded areas slowly healed with depigmentation, milia, and some atrophy. A few new bullae appeared. The patient was discharged from the hospital at 2 months of age. Treatment has
Levitt H. THE LOS ANGELES DERMATOLOGICAL SOCIETY. Arch Dermatol. 1973;107(5):767-768. doi:10.1001/archderm.1973.01620200077023