We studied the frequency of 20 human leukocyte (HL-A) alloantigens in 18 patients with pemphigus. HL-A13 was significantly increased as compared to a normal racial control group. Five of the 18 patients (28%) had HL-A13, whereas only 10 of 251 controls (4%) had the same antigen. Sera from patients did not react with their own lymphocytes nor did they have any anti-HL-A antibodies in lymphocytotoxicity tests. Anti HL-A sera did not react with the pemphigus interepithelial antigen in an indirect immunofluorescent test.
Katz SI, Dahl MV, Penneys N, Trapani RJ, Rogentine N. HL-A Antigens in Pemphigus. Arch Dermatol. 1973;108(1):53-55. doi:10.1001/archderm.1973.01620220025006