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Case Reports
July 1973

Hereditary Papulotranslucent AcrokeratodermaA New Variant of Familial Punctate Keratoderma?

Author Affiliations

From the Department of Dermatology, Harvard Medical School at the Massachusetts General Hospital, Boston.

Arch Dermatol. 1973;108(1):108-110. doi:10.1001/archderm.1973.01620220070020

We have given the name "hereditary papulotranslucent acrokeratoderma" (HPA) to a new syndrome consisting of persistent, asymptomatic, yellowish-white, translucent papules and plaques that appear on the hands and feet, associated with fine-textured scalp hair and atopic diathesis. Histologic study of the translucent lesions showed orthohypergranulosis, acanthosis, and a relatively normal dermis.