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Regular Departments
July 1973

Eosinophilic Ulcer of the Tongue

Arch Dermatol. 1973;108(1):133. doi:10.1001/archderm.1973.01620220087028

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To the Editor.—  We report a case of benign eosinophilic ulcer of the tongue, an affection that remains of unknown cause.A 39-year-old man is admitted for a lingual ulceration, which has appeared spontaneously ten days before admission. In the median part of the tongue, he has an ulceration 11X8 mm (Figure), infiltrated at the base and painful. Palpation shows bilaterally some small submaxillary lymph nodes. Results of clinical examination, as well as the history, are within normal limits. Laboratory data are normal. All serologic and bacteriologic investigations remain negative. Spontaneous resolution occurred after two months. The histologic examination of the lesion shows in the dermis a dense inflammatory infiltrate of polynuclear neutrophils and numerous eosinophils. These eosinophils are revealed by the method of Martinotti. On other places, the infiltrate is mainly histiolymphocytic. There is no sign of malignant tumor.The histologic findings of this lesion and its evolution

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