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Original Contribution
August 1973

Instantaneous Decompression and the Skin

Author Affiliations

Newcastle Upon Tyne, England
From the University Department of Dermatology, Royal Victoria Infirmary, Newcastle Upon Tyne, England.

Arch Dermatol. 1973;108(2):215-217. doi:10.1001/archderm.1973.01620230015005

Suction blister formation in human skin is preceded by intra-epidermal vacuolation, which regresses as the blister forms. The vacuoles are shown to contain fluid, not gas, and probably represent a reaction to injury by suction accompanied by increased permeability of epidermal structures.