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Case Reports
August 1973

Aplasia Cutis Congenita in Three Successive Generations

Author Affiliations

Bronx, NY
From the Department of Medicine, Dermatology Division, Albert Einstein College of Medicine, Bronx Municipal Hospital Center, Bronx, NY.

Arch Dermatol. 1973;108(2):252-253. doi:10.1001/archderm.1973.01620230048016

Aplasia cutis congenita is present at birth and is characterized by small midline posterior ulcers of the scalp that heal with scarring. A significant number of cases have been reported in families; the cases appear to be of autosomal dominant inheritance. This paper highlights the genetic aspect of the disease by presenting three observed cases in three successive generations of one family.