Cicatricial pemphigoid is a chronic, scarring, vesiculobullous eruption, with a theoretical autoimmune cause. It is closely related to bullous pemphigoid, yet unlike bullous pemphigoid, no circulating antibodies have been found. We present here a patient with cicatricial pemphigoid with circulating antibodies to the basement membrane zone of the skin, thus giving more evidence for it being an immunologic disease and for rationale for treatment.
Dantzig P. Circulating Antibodies in Cicatricial Pemphigoid. Arch Dermatol. 1973;108(2):264-266. doi:10.1001/archderm.1973.01620230060023