[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.167.149.128. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Regular Departments
August 1973

Comment on Topical Lomustine Therapy for Psoriasis

Author Affiliations

Philadelphia

Arch Dermatol. 1973;108(2):273. doi:10.1001/archderm.1973.01620230065025

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.

Abstract

To the Editor.—  The paper by Peck et al on topical lomustine therapy for psoriasis, which appeared in the Archives (106:172, 1972), weakens the efforts of those working in the trying area of drug efficacy. This report emphasizes the current need for a cadre of experienced clinical pharmacologists.Though I have no experience with the nitrosoureas, it is a possibility, especially in view of Zackheim's paper in the same issue, that these agents might prove exceedingly beneficial for both psoriasis and mycosis fungoides.To begin with, Peck et al assert that the "double-blind" format was followed. Since lomustine provoked an irritant dermatitis so ferocious as to leave intense hyperpigmentation and telangiectasia, it would seem that the investigators were literally blind. All too often, nowadays, scientists are at pains to show that they have fulfilled the religious requirements of the order that happens to be dominant at the time. In this

First Page Preview View Large
First page PDF preview
First page PDF preview
×