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September 1973

Allergic Contact Dermatitis to Dinitolmide

Author Affiliations

Groningen, Netherlands

Arch Dermatol. 1973;108(3):423-424. doi:10.1001/archderm.1973.01620240069023

To the Editor.—  Commercially prepared animal feed contains several growth stimulants, hormones, vitamins, antiinfectious agents, minerals, antioxidants, and other additives. The handling of the feeds may lead to allergic contact dermatitis to these additives.Recently, Neldner described, in the Archives (106:722-723, 1972), two patients (a 13-year-old girl who fed a pig each day and a 39-year-old hog rancher) who were allergic to tylosin (Tylan) and nitrofurazone (Furacin) present in animal feed. Contact dermatitis to tylosin in animal feed was reported earlier by Preyss1 and to nitrofurazone by Scharfenberg.2 Other animal feed additives to which allergic contact dermatitis have been found to occur are quinoxaline-dioxyde,3 ethoxyquin,4 and cobalt.5 In the present communication we will report a case of contact dermatitis to dinitolmide (Zoalene), a compound added to poultry food to control an outbreak of coccidiosis.

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