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To the Editor.—
Recently at the University of California Medical Center, San Francisco, we saw a 23-year-old man who had developed type 1 herpes simplex virus (HSV) infection of the penis and anus following orogenital sexual contact with a partner who had "cold sores" at the time of contact. This mode of transmission may produce HSV lesions of a different antigenic type than is usually found in the genital area and should be considered in the differential diagnosis of genital and perianal herpetic eruptions.At the time of examination, our patient had multiple 2- to 3-mm tender, grouped vesicles on an erythematous base about the penile corona, the distal shaft of the penis, and the perianal area. Tender, left inguinal lymphadenopathy was present. The history revealed that the patient had had orogenital sexual contact five days prior to appearance of the lesions and ten days before coming to the Dermatology
Hutton RD, Stegman SJ. Herpes Simplex of Penis and Anus. Arch Dermatol. 1973;108(4):580. doi:10.1001/archderm.1973.01620250060024