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November 1973

Gold in the Dermis Following Gold Therapy for Rheumatoid Arthritis

Author Affiliations

Stanford, Calif

From the Department of Dermatology and the Division of Histochemistry, Department of Pathology, Stanford University School of Medicine, Stanford, Calif.

Arch Dermatol. 1973;108(5):655-657. doi:10.1001/archderm.1973.01620260005001

Six patients who had received gold injections for the treatment of rheumatoid arthritis had histologically visible deposits of gold in the skin. In two of the patients, no gold had been administered for 20 years or more. The identity of the deposits was confirmed by emission spectroscopy using a laser microprobe, as well as by their resistance to microincineration and their removal by Lugol solution.