The clinical aspects of and experimental procedures performed on a young woman with localized heat urticaria are described. The few cases reported in the literature do not appear to coincide. Circulation blockage, locally produced or due to a pressure cuff, was the only experimental procedure that prevented the appearance of the reaction. Participation of the kininogen-kinin system in the genesis of increased vascular permeability seems to be a possibility in our patient, who also showed an exaggerated local response to histamine and to the histamine releaser, Compound 48/80.
de Moragas JM, Giménez-Camarasa JM, Noguera J. Localized Heat Urticaria. Arch Dermatol. 1973;108(5):684-686. doi:10.1001/archderm.1973.01620260032010