The sign of Leser-Trélat refers to the sudden appearance and rapid increase in size and number of seborrheic keratoses associated with an internal malignant tumor. The case of a patient who had the sign is reported and previously reported cases are reviewed.
Dantzig PI. Sign of Leser-Trélat. Arch Dermatol. 1973;108(5):700-701. doi:10.1001/archderm.1973.01620260048019