Alopecia, as a manifestation of Hodgkin disease, is a rare occurrence. It may be due to infiltration and follicle destruction by the disease, or it may be a secondary "toxic" manifestation.
The patient had marked alopecia of the scalp several months before any other signs and symptoms of the disease had appeared. The hair loss was characterized as a telogen effluvium. Other cases in the literature regarding hair loss and Hodgkin disease are discussed.
Klein AW, Rudolph RI, Leyden JJ. Telogen Effluvium as a Sign of Hodgkin Disease. Arch Dermatol. 1973;108(5):702-703. doi:10.1001/archderm.1973.01620260050020