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To the Editor.—
Until the precise molecular defects in the hyperlipidemias are defined, we can only speculate on the reasons for the particular morphologic findings and localizations of the clinical lesions in these diseases. Of special interest are the data of Benditt and Benditt (Proc Natl Acad Sci USA 70:1753, 1973) that raised the possibility that skin xanthomas may be monoclonal in origin. As long as descriptive terms do not prejudice us toward a specific hypothesis, we think that the expression intertriginous xanthomas is a relatively safe descriptive term.
Goldsmith LA. Intertriginous Xanthomas-Reply. Arch Dermatol. 1974;109(1):100. doi:10.1001/archderm.1974.01630010072030