A patient had necrotizing vasculitis induced by a contact dermatitis to gold. Repeat patch tests to gold leaf confirmed the diagnosis. The migratory-inhibitory test and the lymphocyte transformation test were negative to gold. Cryoprofibrin levels were elevated, indicating increased intravascular coagulation. Urinary excretion of gold was 16 times higher than normal.
Roenigk HR, Handel D. Gold Vasculitis. Arch Dermatol. 1974;109(2):253-255. doi:10.1001/archderm.1974.01630020065018