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February 1974

Cicatricial Pemphigoid

Arch Dermatol. 1974;109(2):263-264. doi:10.1001/archderm.1974.01630020071027

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To the Editor.—  Since the appearance of the original report by Bean et al (Arch Dermatol 106:195, 1972) and the more recent description by Holubar et al (Arch Dermatol 108:50,1973) of in vivo-fixed basement membrane antibodies in patients with cicatricial pemphigoid, dermatologists have been awaiting a report regarding circulating antibodies in these patients. The recent article by Dr. Dantzig entitled "Circulating Antibodies in Cicatricial Pemphigoid" that appeared in the Archives (108:264,1973) is, on the surface, a fulfillment of this expectation. However, there seems to be a flaw in this report, and it is not, for a change, in the technique of immunofluorescence. The flaw is in the diagnosis. The patient described by Dantzig did have mucosal lesions, but the predominant lesions were apparently those on the skin of the hands, shoulders and chest. It is true that she developed dysphagia and hoarseness and that vocal cord scarring was demonstrated

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