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March 1974

Combined Epidermolytic Hyperkeratosis and Focal Acantholytic Dyskeratosis

Author Affiliations

Miami, Fla; St. Petersburg, Fla

From the departments of dermatology and pathology, University of Miami School of Medicine (Dr. Ackerman) and the St. Petersburg Medical Clinic (Dr. Goldman). Dr. Ackerman is now at

Arch Dermatol. 1974;109(3):385-386. doi:10.1001/archderm.1974.01630030043010

The blending together of epidermolytic hyperkeratosis and focal acantholytic dyskeratosis in the same biopsy specimens exemplifies the lability and variability of epidermal metabolism. A clue to the pathogenesis of these distinctive changes may be contained in this unusual histologic collision.