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To the Editor.—
The issues raised by Drs. Lloyd and Stocker extend well beyond the technical details we present in our paper. Lloyd and Stocker have indeed brought to the fore the questions of greatest concern. Our data merely show that each ingredient of Mycolog Cream has an ascertainable activity when evaluated in a model system. The weaknesses of these particular models are clearly perceived by Lloyd; they certainly do not resemble dermatoses colonized by pathogens. We were measuring prophylactic antimicrobial activity in an artificial system.But now let's get down to the nitty-gritty and examine possible motives for such sharp criticisms. The matter cannot be settled on scientific grounds. None of us have hard facts and that kind of information will not be forthcoming for a long time. The argument really reduces to attitudinal positions and to biases. While the latter are denounced in public places, especially by
Kligman AM. Further Comment on Combinations-Reply. Arch Dermatol. 1974;109(3):410-411. doi:10.1001/archderm.1974.01630030064024