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March 1974


Arch Dermatol. 1974;109(3):416. doi:10.1001/archderm.1974.01630030068025

Unilateral Systematized Hypochromic Nevus. Presented by David L. Cram, MD, Kimie Fukuyama, MD.  A 3-year-old boy of Salvadorian parents had hypopigmented areas that were present on the right side of his trunk at birth. A band of hypopigmented whorls was prominent on the anterior trunk. Similar discontinuous streaks of hypopigmentation were present on the upper portion of the right arm and the right thigh and leg. The overall pattern resembles a negative picture of the pigmentation seen in incontinentia pigmenti (Bloch-Sulzberger disease).The boy's maternal grandfather had a similar lesion on the right side of his abdomen, and his mother had similar but less extensive hypopigmentation of her right leg. The mother's lesion has repigmented substantially.In March 1972, the patient was admitted to hospital for diagnosis of focal seizures of six months' duration. The results of physical examination showed no abnormality, except for the cutaneous changes. Laboratory studies, including

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