Five patients with typical clinical and histologic features of atrophie blanche (livedo reticularis with summer ulcerations) have been observed during the past 2½ years. All of these patients have responded favorably to administration of phenformin and ethylestrenol.
Gilliam JN, Herndon JH, Prystowsky SD. Fibrinolytic Therapy for Vasculitis of Atrophie Blanche. Arch Dermatol. 1974;109(5):664-667. doi:10.1001/archderm.1974.01630050010002