Orally administered flucytosine appeared to successfully eradicate chromomycosis in three patients. The duration of therapy should be adequate for complete clinical and mycological evidence of cure. Flucytosine is easily administered and the untoward effects are minor, infrequent, and easily reversible. Flucytosine appears to be a major improvement over prior therapy for this chronic and progressive disease.
Mauceri AA, Cullen SI, Vandevelde AG, Johnson JE. FlucytosineAn Effective Oral Treatment for Chromomycosis. Arch Dermatol. 1974;109(6):873-876. doi:10.1001/archderm.1974.01630060051015