A patient with relapsing severe orogenital aphthae and cutaneous ulcers consistent with incomplete Behçet syndrome failed to respond to conventional treatment, including continuous orally administered corticosteroid therapy in moderate doses. Having spent little time out of the hospital in the previous two years, she was placed on a regimen of azathioprine, 150 mg daily, in April, 1972. Since September, 1972, she has been free of disease except for occasional short-lived mouth ulcers while her prednisone dose was gradually reduced to 5 mg daily. No serious toxic side effects have developed after 21 months on this regimen.
Nethercott J, Lester RS. Azathioprine Therapy in Incomplete Behçet Syndrome. Arch Dermatol. 1974;110(3):432-434. doi:10.1001/archderm.1974.01630090066014