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October 1974

Contact Dermatitis From Stearyl Alcohol and Propylene Glycol

Author Affiliations

Woodside, Long Island, NY

Arch Dermatol. 1974;110(4):636. doi:10.1001/archderm.1974.01630100084025

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To the Editor.—  In their report titled "Contact Dermatitis from Stearyl Alcohol and Propylene Glycol in Fluocinonide Cream" that appeared in the Archives (109:397, 1974), Drs. Shore and Shelley proved that allergic reactions occurred due to an impurity in stearyl alcohol. These authors mentioned that oleyl alcohol is one of the impurities present in stearyl alcohol. I recently studied an individual who was sensitive to stearyl alcohol and who showed cross-reactions to oleyl alcohol. It is of further interest to note that one popular agent that is used by many dermatologists produced quite a few allergic reactions until the oleyl alcohol was removed. In two of these oleyl-alcohol-sensitive individuals, cross-reactions also occurred with stearyl alcohol.Furthermore, it is of interest to note that Drs. Bandman and Vogel of Munich, Germany (written communication, August, 1970) stated that a stearyl-alcohol-sensitive patient showed cross reactions to panthenol, which is the alcohol of pantothenic

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